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昆蟲細胞培養用培養基 - PSFM-J1 液體培養基
PSFM-J1 液體培養基,是昆蟲細胞 Sf9、High Five(H5)培養用的無血清培養基。[查看]
http://m.baichuan365.com/Article/PSFM-J1_1.html
抗BIF1單克隆抗體(克隆號:BIF1-443)
野生型(left lane)和 Bif-1 缺陷型(right lane)小鼠胚胎成纖維細胞在使用抗 Bif-1 抗體(克隆號:BIF1-443)所得結果,抗體按1:500稀釋,并用含有3%脫脂牛奶的 TBS-T 溶液進行封閉處理。預測條帶大小為 42 kDa 左右[查看]
http://m.baichuan365.com/Article/Anti-BIF1_1.html
肺癌腦轉移的新機制
2023年8月17日,廣州醫科大學何建行及克利夫蘭診所鮑仕登共同通訊在Cancer Cell 在線發表題為“CD44+ lung cancer stem cell-derived pericyte-like cells cause brain metastases through GPR124-enhanced trans-endothelial migration”的研究論文,該研究表明報道了肺腺癌(ADC)中來自CD44+肺癌干細胞(CSCs)的血管周細胞通過G蛋白偶聯受體124 (GPR124)增強的跨內皮遷移(TEM)引起腫瘤腦轉移。[查看]
http://m.baichuan365.com/Article/fanzydxjz_1.html
Nature Medicine發現了新的基因變異,可以預防阿爾茨海默病
通過由哥倫比亞安蒂奧基亞大學的研究人員領導的臨床評估,在Mass Eye and Ear和洛杉磯兒童醫院進行的遺傳和分子研究,在MGH進行的神經成像和生物標志物研究,以及由德國漢堡-埃本多夫大學醫學中心的研究人員進行的神經病理學研究,研究小組確定了一種新的基因變異,可以預防阿爾茨海默病。該變異發生在與2019年報道的同一家族病例不同的基因上,但指出了一種共同的疾病途徑。他們的發現還指出了大腦的一個區域,這個區域可能在未來提供最佳的治療目標。[查看]
http://m.baichuan365.com/Article/naturemedicinefxlxdj_1.html
獻血可以解毒!JAMA子刊:定期獻血可有效減少血液中難以去除的有害氟化物
近日,一篇題為“Effect of Plasma and Blood Donations on Levels of Perfluoroalkyl and Polyfluoroalkyl Substances in Firefighters in Australia”的研究發表于JAMA Network Open。本次研究由澳大利亞科學家Robin Gasiorowski博士及其團隊主導,這項隨機試驗發現定期獻血或獻血漿可顯著降低血液中PFAS水平,其中,獻血漿更有效。[查看]
http://m.baichuan365.com/Article/xxkyjdjamazkdqxxkyxj_1.html
打破固有認知!Science揭秘腸道運行新機制:合成膽固醇中的“好學生”,或為肝臟疾病治療帶來新靶點
近日,華盛頓大學醫學院的研究團隊在Science 發表最新研究 Enterically derived high-density lipoprotein restrains liver injury through the portal vein,該項研究指出,人體的肝臟承擔了在血液中產生與合成大部分高密度脂蛋白的角色,但類似的合成也發生在腸道。研究人員在小腸內發現了一種特殊類型的高密度脂蛋白HDL3,它以HDL的亞種形式存在,會與腸道內的脂多糖炎癥分子結合,阻斷引起肝臟炎癥的細菌信號,以達到保護肝臟的目的。[查看]
http://m.baichuan365.com/Article/dpgyrzsciencejmcdyxx_1.html
Nature 三連重磅!識破癌細胞的“詭計”,為結直腸癌患者帶來新希望
近日, 頂級學術期刊《Nature》三連發表重磅文章拆穿了癌細胞的“把戲”,為結腸癌高危人群提供了新的預防策略。同時,《Nature》還在線發表題為Cancer stem cells in the gut have a bad influence on neighbouringcells的 News & Views,提供了有關癌細胞及其鄰近細胞在腸道中的競爭動態的重要見解。[查看]
http://m.baichuan365.com/Article/natureslzbspaxbdgjwj_1.html
北大科學家發Cell頂刊:通過剪接體抑制劑可使小鼠產生全能干細胞
近日,北京大學的研究人員在《Cell》雜志上在線發表了題為“Mouse totipotent stem cells captured and maintained throughspliceosomal repression”的文章,發現剪接體抑制能夠產生小鼠全能干細胞。[查看]
http://m.baichuan365.com/Article/bdkxjfcelldktgjjtyzj_1.html
JAMA:糖尿病發病年齡越小,患癡呆癥的風險越高
2021年4月27日,法國巴黎大學Archana Singh-Manoux團隊在《美國醫學會雜志》發表了研究成果,題為“Association Between Age at Diabetes Onset and Subsequent Risk of Dementia”,研究了糖尿病發病年齡與癡呆風險的相關性。[查看]
http://m.baichuan365.com/Article/jamatnbfbnlyxhcdzdfx_1.html
癌癥免疫療法副作用不容忽視,不僅要“治”,還要會“防”
近日,麻省總醫院(MGH)的研究人員在《癌癥免疫治療雜志》上發表了一篇文章,深入分析了接受癌癥免疫療法治療后的患者出現免疫相關不良事件(irAE)的發生概率。[查看]
http://m.baichuan365.com/Article/azmylffzybrhsbjyzhyh_1.html
Cell子刊:孕婦肥胖會影響孩子的認知和社交能力障礙!高纖維飲食或能改善恢復!
近日,來自西北農林科技大學和上海交通大學的研究人員在《Cell Metabolism》上發表了題為High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis的研究成果,發現腸道微生物菌群-代謝物-腦軸可能是孕產婦肥胖引起后代認知和社交能力缺陷的基礎,而攝入較高的膳食纖維可能是一種有潛力的干預措施。[查看]
http://m.baichuan365.com/Article/cellzkyffphyxhzdrzhs_1.html
糖尿病患者的福音來了!《BMC》發文:NCAS可作為飲食糖替代品
近日,《BMC》發布了一篇題為High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice的文章,發現人和小鼠短期內食用糖精量在最大可接受水平(ADI)時,不會改變其腸道菌群穩態或引起葡萄糖耐受不良。[查看]
http://m.baichuan365.com/Article/tnbhzdfyllbmcfwncask_1.html
Nature子刊:揭示“顏值”背后的遺傳信息
早期發育過程中胎兒的面部結構往往會融合在一起,那么,后來的發育過程中我們的面部是如何形成,形態結構又是如何隨進化而發生改變的呢?近日,來自美國賓夕法尼亞州立大學的研究人員在《Nature Genetics》上發表了題為Insights into the genetic architecture of the human face的研究成果,使用多變量全基因組關聯研究,對8246例個體進行了薈萃分析,從中確定了203個與正常范圍的面部變異相關的單核苷酸多態性(SNP),為了解個體的遺傳如何協調塑造復雜的形態特征提供了一定的見解。[查看]
http://m.baichuan365.com/Article/naturezkjsyzbhdycxx_1.html
Cell子刊:人類能否戰勝糖尿病?這方面可能要向豬學學了!
近日,國際一流學術期刊《Cell Metabolism》在線發表了上海交通大學附屬第六人民醫院賈偉教授團隊名為“Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism”的研究,揭示豬不易患糖尿病的背后機制:豬膽酸通過不同的TGR5和FXR信號機制來改善葡萄糖穩態。[查看]
http://m.baichuan365.com/Article/cellzkrlnfzstnbzfmkn_1.html
Cell解讀!科學家開發出能觀察和控制大腦神經活性的新工具!
日前,一項刊登在國際雜志Cell上題為“A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion”的研究報告中,來自斯坦福大學等機構的科學家們通過研究開發了一種新型分子探針,其或能幫助揭示大腦思考和記憶的分子機制,這種名為“flicker”(Fast Light and Calcium-Regulated Expression<快速光和鈣調節表達技術>或FLiCRE)的工具或能用于在任何細胞內執行各種研究任務,包括標記、記錄和控制細胞功能等。[查看]
http://m.baichuan365.com/Article/celljdkxjkfcngchkzdn_1.html
記錄總數:97 | 頁數:7  1234567  
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