羧甲基標記聚蔗糖 CM-Polysucrose
羧甲基標記聚蔗糖
羧甲基標記聚蔗糖由羧甲基取代的葡聚糖鏈構成,使其具有多聚陰離子的特點。檢查所有批次的分子量、取代度和干燥失重。TdB提供平均分子量70KDa的羧甲基標記聚蔗糖。羧甲基標記聚蔗糖為白色粉末。
結構
聚蔗糖是由蔗糖與環氧氯丙烷共聚形成的高分子量的蔗糖聚合物。這個分子高度酯化,羥基含量高,在水溶液中有很好的溶解性。在羧甲基標記多糖黃總,羧基含量約為5%,相當于每五個葡萄糖和果糖單位含有一個羧甲基基團。
儲存和穩定性
羧甲基標記聚蔗糖在室溫下儲存于干燥密封良好的容器中,可穩定保存6年以上。
溶解度
羧甲基標記聚蔗糖易溶于水
應用
羧甲基標記聚蔗糖常用于水凝膠。
產品列表
產品編號
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品名
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分子量(kDa)
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包裝
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CM-Polysucrose 70
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70
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1 g
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參考文獻
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Juenet, M. et al. Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin. Biomaterials 156, 204–216 (2018).
Nultsch, K. & Germershaus, O. Silk fibroin degumming affects scaffold structure and release of macromolecular drugs. European Journal of Pharmaceutical Sciences 106, 254–261 (2017).
Käsdorf, B. T. et al. Mucin-Inspired Lubrication on Hydrophobic Surfaces. Biomacromolecules 18, 2454–2462 (2017).
Ficko, B. W., NDong, C., Giacometti, P., Griswold, K. E. & Diamond, S. G. A Feasibility Study of Nonlinear Spectroscopic Measurement of Magnetic Nanoparticles Targeted to Cancer Cells. IEEE Transactions on Biomedical Engineering 64, 972–979 (2017).
Burke, M. et al. Regulation of Scaffold Cell Adhesion Using Artificial Membrane Binding Proteins. Macromolecular Bioscience 17, 1600523 (2017).
Ndong, C. et al. Antibody-mediated targeting of iron oxide nanoparticles to the folate receptor alpha increases tumor cell association in vitro and in vivo. Int J Nanomedicine 10, 2595–2617 (2015).
Terentyeva, T. G. et al. Bioactive flake–shell capsules: soft silica nanoparticles for efficient enzyme immobilization. J. Mater. Chem. B 1, 3248–3256 (2013).
Asgeirsson, D., Venturoli, D., Rippe, B. & Rippe, C. Increased glomerular permeability to negatively charged Ficoll relative to neutral Ficoll in rats. American Journal of Physiology-Renal Physiology 291, F1083–F1089 (2006).
Koltun, M., Nikolovski, J., Strong, K., Nikolic-Paterson, D. & Comper, W. D. Mechanism of hypoalbuminemia in rodents. American Journal of Physiology-Heart and Circulatory Physiology 288, H1604–H1610 (2005).
Landauer, K. et al. Influence of Carboxymethyl Dextran and Ferric Citrate on the Adhesion of CHO Cells on Microcarriers. Biotechnology Progress 19, 21–29 (2003).
Guimarães, M. A. M., Nikolovski, J., Pratt, L. M., Greive, K. & Comper, W. D. Anomalous fractional clearance of negatively charged Ficoll relative to uncharged Ficoll. American Journal of Physiology-Renal Physiology 285, F1118–F1124 (2003).
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