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PROTEOS<font color='red'>TAT</font>(R)熱位移穩(wěn)定性分析試劑盒 - 加速蛋白穩(wěn)定性篩選
PROTEOSTAT(R)?熱位移穩(wěn)定性檢測試劑盒內(nèi)含有一種檢測蛋白聚集的熒光染料，因此可用于監(jiān)測系統(tǒng)熱應(yīng)力條件下的蛋白穩(wěn)定性。通過熱位移分析，可輕松確定大部分蛋白的聚集溫度。[查看]
http://m.baichuan365.com/Article/PROTEOSTAT_Thermal_shift_1.html
可用于活細胞的GST活性檢測探針 DNs-Rh
DNs-Rh是可以在活細胞中觀察Glutathione?S-transferase（GST）酶活性的熒光探針。由于可以根據(jù)GST活性發(fā)出綠色熒光，可用于評價細胞內(nèi)GST的活性。GST亞家族跨度廣泛，可以實現(xiàn)總GST活性的可視化。[查看]
http://m.baichuan365.com/Article/DNs-Rh_1.html
PROTEOS<font color='red'>TAT</font>(R)蛋白質(zhì)聚集標準品
PROTEOSTAT(R)蛋白質(zhì)聚集標準品，是可靠準確地定量溶液中蛋白質(zhì)聚集的理想選擇，用于檢測樣品中低濃度的聚集蛋白[查看]
http://m.baichuan365.com/Article/proteostat_aggregation_standards_1.html
PROTEOS<font color='red'>TAT</font>(R)蛋白質(zhì)重折疊和聚集靈敏試劑盒
PROTEOSTAT(R)蛋白質(zhì)重折疊和聚集靈敏試劑盒，用于確定蛋白質(zhì)重折疊優(yōu)化條件和功能蛋白峰值回收率。[查看]
http://m.baichuan365.com/Article/proteostat-refolding_1.html
PROTEOS<font color='red'>TAT</font>(R)熱位移穩(wěn)定性分析試劑盒
PROTEOSTAT(R)熱位移穩(wěn)定性分析試劑盒內(nèi)含有一種檢測蛋白聚集的熒光染料，因此可用于監(jiān)測系統(tǒng)熱應(yīng)力條件下的蛋白穩(wěn)定性。通過)熱位移分析，可輕松確定大部分蛋白的聚集溫度。聚集溫度是蛋白穩(wěn)定性的指標，可用于優(yōu)化使蛋白聚集最小化的條件，以及鑒定與目標蛋白結(jié)合并賦予結(jié)構(gòu)穩(wěn)定性的配體。[查看]
http://m.baichuan365.com/Article/proteostat-stability_1.html
PROTEOS<font color='red'>TAT</font>(R) 蛋白聚集檢測
PROTEOSTAT(R) Protein Aggregation Assay，內(nèi)含紅色熒光信號染料，可特異性結(jié)合聚集蛋白，進行檢測。具有廣泛的檢測范圍，可有效檢測可見和不可見的蛋白微粒。[查看]
http://m.baichuan365.com/Article/PROTEOSTAT_1.html
基礎(chǔ)科研 | 石墨烯 YYDS！Science Advances：石墨烯生物支架用于抑制器官移植的炎癥反應(yīng)，提高移植細胞的生存率
2021年11月，來自斯坦福的研究者們在Science 子刊上發(fā)表題為：《Localized drug delivery graphene bioscaffolds forcotransplantation of islets and mesenchymal stem cells》的文章，報道了關(guān)于三維支架用于胰島細胞移植的近期工作進展。研究者們開發(fā)了一種可植入的石墨烯生物支架，這種支架具有良好的生物相容性并且可以攜帶地塞米松(Dex)，使其成為局部消炎藥傳遞平臺，避免常規(guī)靜脈注射地塞米松的全身性的副作用，同時能夠精確地調(diào)節(jié)移植微環(huán)境中的炎癥反應(yīng)。[查看]
http://m.baichuan365.com/Article/jckysmxyydssciencead_1.html
妊娠期糖尿病篩查必需空腹進行？NEJM最新研究揭示答案
近日，《新英格蘭醫(yī)學(xué)雜志》在線發(fā)表了美國Kaiser Permanente Northwest健康研究中心Teresa A. Hillier團隊名為“A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening”的研究成果。該研究比較了妊娠期糖尿病的兩種篩查方法，發(fā)現(xiàn)雖然這兩種檢查方式檢出率有差異，但對孕產(chǎn)婦預(yù)后的影響無明顯差異。[查看]
http://m.baichuan365.com/Article/rsqtnbscbxkfjxnejmzx_1.html
抑郁患者慢性疼痛的原因找到了！Nature子刊揭示不同的丘腦皮質(zhì)回路是引起異常性疼痛的基礎(chǔ)
2021年3月8日，中國科學(xué)技術(shù)大學(xué)張智、李娟和晉艷研究團隊合作在出版的《自然-神經(jīng)科學(xué)》雜志上發(fā)表了一項新成果：Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states。他們發(fā)現(xiàn)，不同的丘腦皮質(zhì)回路是由組織損傷和抑郁樣狀態(tài)引起的異常性疼痛的基礎(chǔ)。[查看]
http://m.baichuan365.com/Article/yyhzmxttdyyzdlnature_1.html
糖尿病患者的福音來了！《BMC》發(fā)文：NCAS可作為飲食糖替代品
近日，《BMC》發(fā)布了一篇題為High-dose saccharin supplementation does not induce gut microbiota changes or glucose intolerance in healthy humans and mice的文章，發(fā)現(xiàn)人和小鼠短期內(nèi)食用糖精量在最大可接受水平（ADI）時,不會改變其腸道菌群穩(wěn)態(tài)或引起葡萄糖耐受不良。[查看]
http://m.baichuan365.com/Article/tnbhzdfyllbmcfwncask_1.html
Science：老年人優(yōu)先接種SARS-CoV-2疫苗更可能降低死亡率
近日，《science》雜志發(fā)表了一篇題為Model-informed COVID-19 vaccine prioritization strategies by age and serostatus的文章，通過數(shù)字模型對全球不同國家的不同接種策略的效益做出了預(yù)測，發(fā)現(xiàn)60歲及以上的人群優(yōu)先接種疫苗可以最大程度地減少死亡率。[查看]
http://m.baichuan365.com/Article/sciencelnryxjzsarsco_1.html
Science：新冠突變毒株可能逃避中和抗體治療，包括再生元和禮來的產(chǎn)品
1月25日，美國華盛頓大學(xué)、哈佛醫(yī)學(xué)院布萊格姆婦女醫(yī)院以及霍華德?休斯醫(yī)學(xué)研究所的研究人員在《Science》共同發(fā)布了一項題為“Prospective mapping of viral mutations that escape antibodies used to treat COVID-19”的研究報告。文中繪制了“逃避”現(xiàn)有的主要臨床抗體藥物的病毒突變圖譜，涵蓋再生元的兩款抗體藥物以及禮來的一款抗體藥物，表明這些藥物可能對SARS-CoV-2發(fā)生的一些突變無效。[查看]
http://m.baichuan365.com/Article/sciencexgtbdzkntbzhk_1.html
Science子刊：利用智能手機超靈敏定量檢測唾液中的新冠病毒
根據(jù)一項新的研究，一種基于唾液的便攜式智能手機平臺為COVID-19測試提供了一種超靈敏但易于使用的方法，它可以在15分鐘內(nèi)給出測試結(jié)果，而無需進行當(dāng)前金標準所需的資源密集型實驗室測試。該方法在12名COVID-19感染者和6名健康對照者中進行了測試。相關(guān)研究結(jié)果于2020年12月11日在線發(fā)表在Science Advances期刊上，論文標題為“A smartphone-read ultrasensitive and quantitative saliva test for COVID-19”。論文通訊作者為美國杜蘭大學(xué)醫(yī)學(xué)院的Tony Y. Hu博士。[查看]
http://m.baichuan365.com/Article/sciencezklyznsjclmdl_1.html
Science子刊解讀！空氣污染真會讓COVID-19的流行變得更加致命嗎？
近日，一篇刊登在國際雜志Science Advances上題為“Air pollution and COVID-19 mortality in the United States： Strengths and limitations of an ecological regression analysis”的研究報告中，來自哈佛大學(xué)陳曾熙公共衛(wèi)生學(xué)院等機構(gòu)的科學(xué)家們通過研究發(fā)現(xiàn)，長期暴露于空氣污染物中的人群或許更易死于COVID-19。在對美國超過3000個縣的分析中，研究人員發(fā)現(xiàn)，長期暴露于細小顆粒物（PM2.5）的暴露量只要發(fā)生小幅增加，人群死于COVID-19的風(fēng)險就會增加10%以上。[查看]
http://m.baichuan365.com/Article/sciencezkjdkqwrzhrco_1.html
Mol Psych：研究揭示S<font color='red'>TAT</font>3有助于調(diào)節(jié)情緒
大量科學(xué)研究表明，炎癥過程在精神疾病的發(fā)展中起著關(guān)鍵作用。特別感興趣的領(lǐng)域之一IL-6 / STAT3信號轉(zhuǎn)導(dǎo)途徑，其與抑郁癥，精神分裂癥和雙相情感障礙有關(guān)。在《Molecular Psychiatry》雜志上發(fā)表的一項研究中，由神經(jīng)生理學(xué)和神經(jīng)藥理學(xué)部的Daniela Pollak領(lǐng)導(dǎo)的MedUni Vienna研究人員表明，STAT3作為一種控制情緒反應(yīng)的分子，在傳遞5-羥色胺相關(guān)信號系統(tǒng)中起著重要作用。[查看]
http://m.baichuan365.com/Article/molpsychyjjsstat3yzy_1.html
記錄總數(shù)：177 | 頁數(shù)：12  <...3456789101112  
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