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西寶生物
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超能力!<font color='red'>ACE</font>2受體蛋白“納米囊泡”可防治新冠
新冠肺炎患者的血液中存在含有血管緊張素轉(zhuǎn)化酶2蛋白的天然納米級大小的囊泡-evACE2,它具有先天廣譜抗病毒機制,可阻止廣泛的新冠病毒毒株感染。[查看]
http://m.baichuan365.com/Article/cnlace2stdbnmnpkfzxg_1.html
Cell揭示:“免疫豁免”的中樞神經(jīng)系統(tǒng),為何能夠受到神經(jīng)免疫攻擊?
越來越多證據(jù)表明,中樞神經(jīng)系統(tǒng)(CNS)并非是一片不會發(fā)生免疫反應(yīng)的“凈土”,許多中樞神經(jīng)系統(tǒng)疾病都與免疫異常有關(guān)。近日,《Cell》雜志在線發(fā)表了美國圣路易斯華盛頓大學(xué)的研究人員帶來的名為“Functional characterization of the duralsinuses as a neuroimmune interface”的合作研究。該研究證明了腦脊液(CSF)中CNS來源的抗原積聚在硬腦膜竇周圍,被局部抗原呈遞細(xì)胞捕獲并呈遞給巡邏的T細(xì)胞。[查看]
http://m.baichuan365.com/Article/celljsmyhmdzssjxtwhn_1.html
Viruses揭示:新冠病毒可藏匿于小鼠大腦,或能解釋COVID-19患者康復(fù)后病情復(fù)發(fā)之謎
近日, Viruses發(fā)表了一篇題為Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice的文章,發(fā)現(xiàn)SARS-CoV-2鼻內(nèi)感染K18-hACE2小鼠會引起嚴(yán)重的神經(jīng)系統(tǒng)疾病。[查看]
http://m.baichuan365.com/Article/virusesjsxgbdkcnyxsd_1.html
咽喉不適?BMJ發(fā)文:這類藥物可能無益于治療持續(xù)性咽喉癥狀
近日,英國紐卡斯?fàn)柛ダ锫t(yī)院的研究人員在《英國醫(yī)學(xué)雜志》(BMJ)上發(fā)表了一篇題為Use of proton pump inhibitors to treat persistent throat symptoms: multicentre, double blind, randomised, placebo controlled trial的文章,研究了質(zhì)子泵抑制劑治療持續(xù)性咽喉癥狀的療效。[查看]
http://m.baichuan365.com/Article/yhbsbmjfwzlywknwyyzl_1.html
Nature子刊:揭示“顏值”背后的遺傳信息
早期發(fā)育過程中胎兒的面部結(jié)構(gòu)往往會融合在一起,那么,后來的發(fā)育過程中我們的面部是如何形成,形態(tài)結(jié)構(gòu)又是如何隨進化而發(fā)生改變的呢?近日,來自美國賓夕法尼亞州立大學(xué)的研究人員在《Nature Genetics》上發(fā)表了題為Insights into the genetic architecture of the human face的研究成果,使用多變量全基因組關(guān)聯(lián)研究,對8246例個體進行了薈萃分析,從中確定了203個與正常范圍的面部變異相關(guān)的單核苷酸多態(tài)性(SNP),為了解個體的遺傳如何協(xié)調(diào)塑造復(fù)雜的形態(tài)特征提供了一定的見解。[查看]
http://m.baichuan365.com/Article/naturezkjsyzbhdycxx_1.html
Cell子刊:顛覆現(xiàn)有理論!過氧化氫讓腸道細(xì)菌遠離結(jié)腸內(nèi)壁
在一項新的研究中,來自美國加州大學(xué)戴維斯分校的研究人員發(fā)現(xiàn)結(jié)腸內(nèi)壁中的一種酶會釋放出過氧化氫---一種已知的消毒化合物--來保護身體免受腸道微生物的侵害。這一研究結(jié)果揭示了微生物在結(jié)腸中的空間分布方式,同時也為開發(fā)一種治療腸道炎癥的新方法奠定基礎(chǔ)。相關(guān)研究結(jié)果發(fā)表在2020年12月9日的Cell Host & Microbe期刊上,論文標(biāo)題為“Anaerobic Respiration of NOX1-Derived Hydrogen Peroxide Licenses Bacterial Growth at the Colonic Surface”。[查看]
http://m.baichuan365.com/Article/cellzkdfxyllgyhqrcdx_1.html
Nature:揭示SARS-CoV-2刺突蛋白結(jié)合人<font color='red'>ACE</font>2受體的結(jié)構(gòu)機制
在一項新的研究中,來自英國弗朗西斯-克里克研究所的研究人員發(fā)現(xiàn)位于SARS-CoV-2冠狀病毒表面上的刺突蛋白(S蛋白)與人類病毒受體ACE2接觸時,可以采取至少十種不同的結(jié)構(gòu)狀態(tài)。這種對感染機制的新見解為開發(fā)疫苗和治療方法奠定基礎(chǔ)。相關(guān)研究結(jié)果于2020年9月17日在線發(fā)表在Nature期刊上,論文標(biāo)題為“Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion”。[查看]
http://m.baichuan365.com/Article/naturejssarscov2ctdb_1.html
EJPS:研究者們開發(fā)出新型抗炎藥物
在最近一項研究中,馬丁·路德大學(xué)藥物學(xué)研究所的研究人員Halle-Wittenberg等人開發(fā)了一種生產(chǎn)質(zhì)量可控的抗炎藥物的方法。由于人體不會將其識別為異物,因此它們比布洛芬或雙氯芬酸等抗炎藥更具優(yōu)勢。結(jié)果發(fā)表在《European Journal of Pharmaceutical Sciences.》上。[查看]
http://m.baichuan365.com/Article/ejpsyjzmkfcxxkyyw_1.html
Cell:深度突變掃描揭示新冠病毒S蛋白受體結(jié)合結(jié)構(gòu)域突變對S蛋白折疊和結(jié)合<font color='red'>ACE</font>2的影響
在一項新的研究中,美國霍華德-休斯醫(yī)學(xué)研究所研究員Jesse Bloom和他的同事們已經(jīng)將近4000種不同的突變?nèi)绾胃淖兞薙ARS-CoV-2與人類細(xì)胞結(jié)合的能力進行了編目。[查看]
http://m.baichuan365.com/Article/cellsdtbsmjsxgbdsdbs_1.html
Science:利用經(jīng)過基因改造的人<font color='red'>ACE</font>受體作為誘餌引誘新冠病毒,阻斷感染
新型冠狀病毒SARS-CoV-2導(dǎo)致2019年冠狀病毒?。–OVID-19),如今正在全球肆虐。隨著COVID-19疫情持續(xù)蔓延,科學(xué)家和醫(yī)療服務(wù)提供者正在尋找方法,以防止這種冠狀病毒暴露后感染組織。[查看]
http://m.baichuan365.com/Article/sciencelyjgjygzdrace_1.html
Cell:小鼠SARS-CoV-2感染模型揭示中和抗體的保護作用
嚴(yán)重急性呼吸綜合征2型冠狀病毒(SARS-CoV-2)已造成數(shù)百萬人感染的大流行。在評估抑制SARS-CoV-2感染和改善疾病的潛在療法和疫苗時,一個限制是缺乏大量易感的小動物模型。商業(yè)可用的實驗室小鼠不容易感染SARS-CoV-2,因為它們的血管緊張素轉(zhuǎn)換酶2 (angiotensin-converting enzyme 2,ACE2)受體存在物種特異性差異。[查看]
http://m.baichuan365.com/Article/cellxssarscov2grmxjs_1.html
西寶生物推薦:2019-nCoV新型冠狀病毒診斷及感染人的關(guān)鍵靶點<font color='red'>ACE</font>-2檢測核心原料
各研究結(jié)果表明,ACE-2受體是新型冠狀病毒感染人類的關(guān)鍵靶點,由此可見,通過阻斷冠狀病毒與ACE-2受體的結(jié)合是治療研究方向之一。西寶生物為2019-nCoV抗病毒研究提供多種科研試劑與原料,共同努力![查看]
http://m.baichuan365.com/Article/xbswtj2019ncovxxgzbd_1.html
【診斷試劑原料】生化診斷校準(zhǔn)品和質(zhì)控品(<font color='red'>ACE</font>、AFU、GDPA、NAG)
在體外診斷試劑的研發(fā)生產(chǎn)中,校準(zhǔn)品和質(zhì)控品是實現(xiàn)體外診斷試劑臨床檢測及監(jiān)督檢驗結(jié)果準(zhǔn)確一致的主要工具,也是保證量值傳遞的實物計量標(biāo)準(zhǔn)。西寶生物推出生化診斷校準(zhǔn)品和質(zhì)控品,包括血管緊張素轉(zhuǎn)換酶(ACE)、巖藻糖苷酶(AFU)、甘氨酰脯氨酰- 二肽氨基肽酶(GDPA酶)、beta-N-乙酰氨基葡萄糖苷酶(NAG),咨詢熱線400-021-8158.[查看]
http://m.baichuan365.com/Article/shzdxzphzkpaceafugdp_1.html
Neurology:太低的LDL膽固醇可能會增加出血性中風(fēng)的風(fēng)險
目前的指南建議降低膽固醇,以降低心臟病風(fēng)險。在一項新的為期9年的研究中,來自中國和美國的研究人員研究了低密度脂蛋白膽固醇(LDL)---通常稱為“壞”膽固醇---與出血性中風(fēng)之間的關(guān)系,結(jié)果發(fā)現(xiàn)如果膽固醇下降過低,這可能會增加出血性中風(fēng)的風(fēng)險。當(dāng)血管在大腦中爆裂時,這種類型的中風(fēng)就會發(fā)生。相關(guān)研究結(jié)果于2019年7月2日在線發(fā)表在Neurology期刊上,論文標(biāo)題為“Low-density lipoprotein cholesterol and risk of intracerebral hemorrhage”。[查看]
http://m.baichuan365.com/Article/neurologytddldldgckn_1.html
【新品發(fā)布】糖尿病領(lǐng)域新秀—Exendin-4 酶免試劑盒全新上市
Exendin-4由39個氨基酸殘基組成,與胰高血糖素樣肽1(GLP-1)有53%的同源性,是GLP-1受體激動劑,與GLP-1類似,Exendin-4可調(diào)節(jié)血糖濃度,但GLP-1的半衰期僅有2min,而Exendin-4半衰期卻長達9.57h,因此在治療2型糖尿病方面具有廣闊的前景。西寶生物可提供用于相關(guān)藥發(fā)生產(chǎn)的Phoenix Pharmaceuticals品牌Exendin-4 (Heloderma suspectum) EIA Kit用于EIA酶免疫實驗,用于實驗室快速檢測艾塞那肽。訂購咨詢熱線:400-021-8158![查看]
http://m.baichuan365.com/Article/xpfbexendin4mmsjh_1.html
記錄總數(shù):629 | 頁數(shù):42  <...33343536373839404142  
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Blood group H antigen pentaose type 1-Nacetyl-Spacer 3-Biotin
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6GrA1-NAc-spacer3-Biotin
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Acetate 100ppm in H2O
Acetate 100ppm in H2O
Acetaldehyde
Acetaldehyde
Trace Elements in White Rice Flour Set(Cd Level I&II)
Trace Elements in White Rice Flour Set(Cd Level I&II)
Trace Elements in Tea Leaf Powder
Trace Elements in Tea Leaf Powder
Trace Elements, Arsenobetaine anc jrcury in Swordfish Tissue
Trace Elements, Arsenobetaine anc jrcury in Swordfish Tissue
Trace Elements and Arsenic Compounds in Seaweed (Hijiki)
Trace Elements and Arsenic Compounds in Seaweed (Hijiki)
Trace Elements, Arsenobetaine and Methylmercury in Cod Fish Tissue
Trace Elements, Arsenobetaine and Methylmercury in Cod Fish Tissue
Trace Elements in Lake Sediment
Trace Elements in Lake Sediment
Trace Elements in River Water (Elevated Level)
Trace Elements in River Water (Elevated Level)
Trace Elements in Marine Sediment
Trace Elements in Marine Sediment
Melting Point Standard Set Vanillin (81-83°C) Phenacetin (134-136°C)°Caffeine (235-237°C)
Melting Point Standard Set Vanillin (81-83°C) Phenacetin (134-136°C)°Caffeine (235-237°C)
Tributyltin(IV) Acetate
Tributyltin(IV) Acetate
N, N-Dimethylaceatamide
N, N-Dimethylaceatamide
N, N-Dimethylaceatamide
N, N-Dimethylaceatamide
Acetic Acid, CH3COOH, 20% v/v
Acetic Acid, CH3COOH, 20% v/v
Mobile Phase Buffer pH 4.5 - Sodium Acetate Trihydrate
Mobile Phase Buffer pH 4.5 - Sodium Acetate Trihydrate
Mobile Phase Buffer pH 4.5 - Sodium Acetate Trihydrate
Mobile Phase Buffer pH 4.5 - Sodium Acetate Trihydrate
Zinc Acetate 10% w/v
Zinc Acetate 10% w/v
Sodium Acetate, 0.2M
Sodium Acetate, 0.2M
Sodium Acetate, 2M
Sodium Acetate, 2M
Acetonitrile, 50% v/v
Acetonitrile, 50% v/v
Lead Acetate Solution (CH COO) Pb, 10%
Lead Acetate Solution (CH COO) Pb, 10%
APDC Butyl Acetate-Ethanol Reagent
APDC Butyl Acetate-Ethanol Reagent
N-Acetyl-L-Cysteine,crystallizate
N-Acetyl-L-Cysteine,crystallizate
N-Acetylneuraminic acid aldolase
N-Acetylneuraminic acid aldolase
N-Acetylneuraminic acid aldolase
N-Acetylneuraminic acid aldolase
Oxaloacetate Decarboxylase
Oxaloacetate Decarboxylase
Acetate-CoA Ligase (Acetyl-CoA Synthetase),from yeast, lyophilizate
Acetate-CoA Ligase (Acetyl-CoA Synthetase),from yeast, lyophilizate
Acetate-CoA Ligase (Acetyl-CoA Synthetase),from microorganism, lyophilizate
Acetate-CoA Ligase (Acetyl-CoA Synthetase),from microorganism, lyophilizate
Cholesterol Esterase, from Candida cylindracea, lyophilizate
Cholesterol Esterase, from Candida cylindracea, lyophilizate
Cholesterol Esterase, from Candida cylindracea, solution
Cholesterol Esterase, from Candida cylindracea, solution
CMP-N-Acetylneuraminic Acid,sodium salt
CMP-N-Acetylneuraminic Acid,sodium salt
UDP-N-Acetylglucosamine,disodium salt
UDP-N-Acetylglucosamine,disodium salt
Ethyclozate metabolite (CIA:5-Chloro-3 (1H)-indazolacetate)
Ethyclozate metabolite (CIA:5-Chloro-3 (1H)-indazolacetate)
ACE5599
ACE5599
N-Chloroacetyl-2,6-diethylaniline
N-Chloroacetyl-2,6-diethylaniline
Ethylene glycol bis (trichloroacetate)
Ethylene glycol bis (trichloroacetate)
Presep(R) Diatomaceous Earth, Granular (Column Volume 15mL)
Presep(R) Diatomaceous Earth, Granular (Column Volume 15mL)
Presep(R) Diatomaceous Earth, Granular (Column Volume 6ml)
Presep(R) Diatomaceous Earth, Granular (Column Volume 6ml)
USP Solution Acetate Buffer TS Conforms to USP 34
USP Solution Acetate Buffer TS Conforms to USP 34
USP Solution Acetate Buffer TS Conforms to USP 34
USP Solution Acetate Buffer TS Conforms to USP 34
USP Solution Acetic Acid 2.00 Normal Conforms to USP 34
USP Solution Acetic Acid 2.00 Normal Conforms to USP 34
USP Solution Acetic Acid 2.00 Normal Conforms to USP 34
USP Solution Acetic Acid 2.00 Normal Conforms to USP 34
USP Solution Acetic Acid-Ammonium Acetate Buffer TS Conforms to USP 34
USP Solution Acetic Acid-Ammonium Acetate Buffer TS Conforms to USP 34
USP Solution Acetic Acid-Ammonium Acetate Buffer TS Conforms to USP 34
USP Solution Acetic Acid-Ammonium Acetate Buffer TS Conforms to USP 34
USP Solution Cupric Acetate TS Conforms to USP 34
USP Solution Cupric Acetate TS Conforms to USP 34
USP Solution Cupric Acetate TS Conforms to USP 34
USP Solution Cupric Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Potassium Acetate TS Conforms to USP 34
USP Solution Potassium Acetate TS Conforms to USP 34
USP Solution Potassium Acetate TS Conforms to USP 34
USP Solution Potassium Acetate TS Conforms to USP 34
USP Solution Sodium Acetate TS Conforms to USP 34
USP Solution Sodium Acetate TS Conforms to USP 34
USP Solution Sodium Acetate TS Conforms to USP 34
USP Solution Sodium Acetate TS Conforms to USP 34
European Pharmacopoeia Reagent Acetic acid (30%)
European Pharmacopoeia Reagent Acetic acid (30%)
European Pharmacopoeia Reagent Acetic acid, Dilute (12%)
European Pharmacopoeia Reagent Acetic acid, Dilute (12%)
European Pharmacopoeia Reagent Acetic anhydride Solution R1
European Pharmacopoeia Reagent Acetic anhydride Solution R1
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopeoia Lead Acetate Solution
European Pharmacopeoia Lead Acetate Solution
European Pharmacopoeia Reagent Methoxyphenylacetic reagent
European Pharmacopoeia Reagent Methoxyphenylacetic reagent
European Pharmacopoeia Reagent Thioacetamide Solution
European Pharmacopoeia Reagent Thioacetamide Solution
European Pharmacopoeia Reagent Zinc acetate Solution
European Pharmacopoeia Reagent Zinc acetate Solution
European Pharmacopoeia Reagent Buffered acetone Solution
European Pharmacopoeia Reagent Buffered acetone Solution
European Pharmacopoeia Reagent Acetate Buffer Solution PH4.6
European Pharmacopoeia Reagent Acetate Buffer Solution PH4.6
6-Acetylcodeine,1.0mg/mL 于乙腈
6-Acetylcodeine,1.0mg/mL 于乙腈
Acesulfame potassium impurity B
Acesulfame potassium impurity B
Trace Elements in Water 標(biāo)準(zhǔn)物質(zhì)
Trace Elements in Water 標(biāo)準(zhǔn)物質(zhì)
Androsterone 3-acetate,certified
Androsterone 3-acetate,certified
Corticosterone-21-acetate
Corticosterone-21-acetate