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P<font color='red'>NAS</font>突破性新發現:幫助細菌在人類呼吸道定植的CPS特征
新加坡國立大學醫學院(NUS Medicine)的科學家們在一項突破性的發現中,發現了幫助細菌在人類呼吸道定植的CPS的特征。研究表明,CPS膠囊的結構及其連接和組合類型在允許細菌更好地附著在人類上呼吸道和下呼吸道內壁上并存活方面起著重要作用。[查看]
http://m.baichuan365.com/Article/pnastpxxfxbzxjzrlhxd_1.html
CAR-T療法創始人P<font color='red'>NAS</font>發文:實體腫瘤治療曙光出現?利用“組合拳”幫助T細胞
發表在《美國國家科學院院刊》(PNAS)上的研究結果表明,靶向控制炎癥相關基因功能的兩種調節因子,可使模型中的T細胞至少增加10倍,從而增強抗腫瘤免疫活性和持久性。[查看]
http://m.baichuan365.com/Article/cartlfcsrpnasfwstzlz_1.html
《P<font color='red'>NAS</font>》科學家解開細胞存活之謎
拉霍亞免疫研究所(LJI)的研究人員終于發現了一種名為O-GlcNAc轉移酶(OGT)的酶在維持細胞健康中的作用。這些發現發表在《美國國家科學院院刊》(Proceedings of The National Academies of Sciences)上,為細胞生物學提供了至關重要的見解,并可能為重大醫學突破鋪平道路。[查看]
http://m.baichuan365.com/Article/pnaskxjjkxbchzm_1.html
《Cell》深度挖掘人類RNA病毒的遠親——類病毒
一組研究人員開發了一種計算方式,以識別和更好地理解類病毒和類病毒共價封閉環狀RNA (cccRNAs,也簡稱為環狀RNAs)。[查看]
http://m.baichuan365.com/Article/cellsdwjrlrnabddyqlb_1.html
P<font color='red'>NAS</font>:最新發現!常見的甜味劑阿斯巴甜或與焦慮癥發生直接相關
來自佛羅里達州立大學等機構的科學家們通過研究發現了名為阿斯巴甜(aspartame)的人工甜味劑或與小鼠機體出現的焦慮癥樣行為有關,阿斯巴甜是一種在近5000種減肥食物和飲料中所使用的人工甜味劑。[查看]
http://m.baichuan365.com/Article/pnaszxfxcjdtwjasbthy_1.html
《P<font color='red'>NAS</font>》首次發現,一種專吃病毒為生的微生物
內布拉斯加-林肯大學的研究人員發現,微小的纖毛蟲可以吃掉大量與它們共享水生棲息地的傳染性氯病毒,這是一個值得《吃豆人》的轉折。該團隊的實驗室實驗還首次表明,只含病毒的飲食(該團隊稱之為“病毒性”)足以促進生物體的生理生長,甚至種群增長。[查看]
http://m.baichuan365.com/Article/pnasscfxyzzcbdwsdwsw_1.html
研究人員發現了非酒精性脂肪性肝炎的新分子靶點
來自復旦大學中山醫院和上海交通大學附屬第六人民醫院的研究人員和其他合作者,通過三種飲食或化合物誘導的小鼠慢性肝炎癥和損傷模型,共同確定了NASH發病的一種新的分子機制。本研究證實了IGF2BP2是NASH發生發展過程中的關鍵調控因子。[查看]
http://m.baichuan365.com/Article/yjryfxlfjjxzfxgydxfz_1.html
P<font color='red'>NAS</font>揭示了人類內源性逆轉錄酶的結構
根據羅格斯大學的一項研究表明,人類內源性逆轉錄酶的晶體結構與HIV逆轉錄酶相似,HIV逆轉錄酶是一種眾所周知的易處理藥物靶標,它將有助于設計治療癌癥和其他疾病的藥物。[查看]
http://m.baichuan365.com/Article/pnasjslrlnyxnzlmdjg_1.html
六年半攻關!華東師大科學家P<font color='red'>NAS</font>發文:給細胞“喝紅酒”可調控腫瘤免疫治療
近日,華東師范大學生命科學學院、上海市調控生物學重點實驗室、華東師范大學醫學合成生物學研究中心葉海峰研究員團隊經過六年半科研攻關,聯合在《PNAS》雜志發表了一篇文章,該研究為如何緩解CAR-T療法中的細胞因子風暴、腫瘤溶解綜合征等致命副作用提供了新的思路。[查看]
http://m.baichuan365.com/Article/qhkystcartxblfzwsylz_1.html
P<font color='red'>NAS</font>驚人大發現!發燒竟能抗癌,“小病不斷,大病不犯”或許不是謠傳
近日,德國馬克斯·普朗克免疫生物學和表觀遺傳學研究所Erika L. Pearce教授領銜的研究團隊對這一疑問進行了科學的解答,該團隊在《PNAS》雜志發表了一篇重要成果,發現機體體溫的升高有益于優化CD8+T細胞的代謝活性和功能,增強線粒體蛋白的翻譯效率,從而有效抵御癌細胞的侵襲。[查看]
http://m.baichuan365.com/Article/pnasjrdfxfsjnkaxbbdd_1.html
Nature:被譽為“抗癌明星”的免疫療法,可能是這類癌癥患者的“催命符”
當地時間3月24日,由生物制藥公司諾和諾德的Dominik Pfister領銜在《Nature》發表了一篇題為NASH limits anti-tumour surveillance in immunotherapy-treated HCC的文章,揭示了免疫療法在HCC患者中產生不同療效的原因。[查看]
http://m.baichuan365.com/Article/naturebywkamxdmylfkn_1.html
新研究發現:人造甜味劑會促進全身炎癥和脂肪肝的發展,不過有一種甜味劑例外…
近日,來自中國科學院精密測量科學與技術創新研究院和美國賓夕法尼亞州立大學的研究人員在《mSystems》上發表研究成果,發現NAS的攝入會顯著減少小鼠腸道菌群中阿克曼氏菌的豐度,并降低芳香烴受體(AHR)激動劑水平,促進全身炎癥和脂肪肝的發展。而另一種對健康無明顯影響的天然甜味劑(新橙皮苷二氫查耳酮)或許能作為NAS和糖的替代品。[查看]
http://m.baichuan365.com/Article/xyjfxrztwjhcjqsyzhzf_1.html
Viruses揭示:新冠病毒可藏匿于小鼠大腦,或能解釋COVID-19患者康復后病情復發之謎
近日, Viruses發表了一篇題為Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice的文章,發現SARS-CoV-2鼻內感染K18-hACE2小鼠會引起嚴重的神經系統疾病。[查看]
http://m.baichuan365.com/Article/virusesjsxgbdkcnyxsd_1.html
P<font color='red'>NAS</font>:黑人新生兒在白人醫生的照護下死亡的可能性要高出三倍
在一項新的研究中,來自美國多家研究機構的研究人員發現與美國全國平均水平相比,新生的黑人嬰兒當由白人醫生照護時,剛出生就死亡的可能性要高出3倍。相關研究結果近期發表在PNAS期刊上,論文標題為“Physician–patient racial concordance and disparities in birthing mortality for newborns”。在這篇論文中,他們描述了他們對佛羅里達州醫療記錄和照顧新生兒的醫生種族的研究,以及他們取得的發現。[查看]
http://m.baichuan365.com/Article/pnashrxsezbrysdzhxsw_1.html
P<font color='red'>NAS</font>:解讀!科學家們有望利用一種新型的聚糖標記策略來揭秘肝臟中的免疫激活機制!
人類細胞會被一層膜包裹著,膜上覆蓋有多種稱之為聚糖(glycans)的糖分子,這些聚糖分子在機體健康和疾病發生過程中扮演著非常關鍵的作用,因此了解其特性就顯得尤為重要了,由于其獨特之處,科學家們并沒有太多工具來研究聚糖分子的功能以及其在機體中的相互作用。[查看]
http://m.baichuan365.com/Article/pnasjdkxjmywlyyzxxdj_1.html
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Glucose Dehydrogenase Amano 2
Lactate Dehydrogenase Amano 3
Lactate Dehydrogenase Amano 3
Malate Dehydrogenase Amano 3
Malate Dehydrogenase Amano 3
Penicillinase
Penicillinase
Penicillinase Bulk Powder
Penicillinase Bulk Powder
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactateoxidase),from Pediococcus species, lyophilizate
Lactate 2-Monooxygenase (Lactateoxidase),from Pediococcus species, lyophilizate
Mab<CK-MM> Mix creatinine kinase isoenzyme MM
Mab Mix creatinine kinase isoenzyme MM
Creatine Kinase-MM Monoclonal Antibody (14.15)
Creatine Kinase-MM Monoclonal Antibody (14.15)
Creatine Kinase-MM Monoclonal Antibody (14.5)
Creatine Kinase-MM Monoclonal Antibody (14.5)
Creatine Kinase-MM Monoclonal Antibody (14.52)
Creatine Kinase-MM Monoclonal Antibody (14.52)