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Science:重磅!突破性的HIV疫苗設計策略嶄露頭角
在一項新的研究中,來自美國斯克里普斯研究所等研究機構的研究人員成功地對一種先進的HIV疫苗策略進行了原理驗證,這種方法也可能有效地保護人們免受其他他致命性傳染病的侵害。相關研究結果近期發表在Science期刊上,論文標題為“A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses”。[查看]
http://m.baichuan365.com/Article/sciencezbtpxdhivymsj_1.html
【外泌體純化】新型親和法外泌體提取試劑盒 ——MagCapture 外泌體提取試劑盒PS
MagCapture™外泌體提取試劑盒 PS采用磷酯酰絲氨酸(PS)親和Tim4蛋白固化磁珠(PS親和法)的方法可以簡便快捷地提取高純度的完整外泌體和其他細胞外囊泡(EVs)。如果想要得到更高純度的外泌體,請使用10,000×g離心后的上清。西寶生物作為Wako指定國內經銷商可提供外泌體研究整體解決方案,咨詢請撥打400-021-8158[查看]
http://m.baichuan365.com/Article/xxqhfwmttqsjhmagcapt_1.html
二噁英分析專用硅膠填料
西寶生物攜手wako二噁英分析產品線也已服務于國內客戶近十年,為國內二噁英檢測分析提供整體的解放方案,除了能提供用于二噁英分析用吸附柱,還提供能用于填充柱子中的二噁英吸附填料。包括用于二噁英吸附的吸附樹脂(Dioxin Trap Beads),用于制備多層硅膠柱的2%氫氧化鉀硅膠、10%硝酸銀硅膠、44% 硫酸硅膠、22% 硫酸硅膠、硫酸鈉等,用于制備活性炭埋藏硅膠柱的活性炭埋藏硅膠等。這些填料都具有良好的滲透性和對二噁英的良好吸附能力。[查看]
http://m.baichuan365.com/Article/efyfxzygjtl_1.html
Adv Sci:研究人員描述了一種誘導癌細胞自我殺傷的機制
研究人員描述了一種新的機制,通過干擾離子穩態誘導癌細胞的自我殺傷。韓國科學技術研究院生化工程系的一個研究小組開發了螺旋多肽鉀離子載體,可導致程序性細胞死亡。離子載體增加活性氧濃度,使內質網應激至細胞死亡。[查看]
http://m.baichuan365.com/Article/advsciyjrymslyzydaxb_1.html
CMGH:揭秘慢性胰腺炎誘發胰腺癌發生的分子機制
慢性胰腺炎(CP,Chronic pancreatitis)是誘發胰腺導管腺癌(PDAC,pancreatic ductal adenocarcinoma)的易感因素,PDAC是一種最常見且最具致死性的胰腺癌,目前研究人員并不清楚慢性胰腺炎和胰腺導管腺癌之間的關聯。[查看]
http://m.baichuan365.com/Article/cmghjmmxyxyyfyxafsdf_1.html
Science子刊:HIV疫苗新策略!利用抗獨特型抗體激活表達廣泛中和抗體的前體B細胞
誘導保護性的廣泛中和抗體(broadly neutralizing antibody, bNAb)產生是成功接種疫苗的關鍵策略。然而,對于許多重要的全球性疾病,如艾滋病和流感,人們尚未實現高效的疫苗接種[查看]
http://m.baichuan365.com/Article/sciencezkhivymxcllyk_1.html
Nat Commun:HIV研究新發現!CD11c+樹突細胞或是機體HIV感染的一線免疫細胞
近日,一項刊登在國際雜志Nature Communications上的研究報告中,來自西米德醫學研究所(Westmead Institute for Medical Research)的科學家們通過研究發現,全新的免疫細胞或許處于HIV感染的前線,這些名為CD11c+的樹突細胞對于HIV的感染非常易感,而且能將病毒傳染給其它細胞。[查看]
http://m.baichuan365.com/Article/natcommunhivyjxfxcd1_1.html
【每周優選】神經退行性疾病研究—小膠質/巨噬細胞特異性蛋白抗Iba1抗體
Iba1:ionized calcium binding adapter molecule 1小膠質細胞/巨噬細胞特異性蛋白抗體,Iba 1是在巨噬細胞/小膠質細胞中特異性表達的分子量為17,000的鈣結合蛋白。此蛋白質通常稱為中樞神經系統中的小膠質細胞標記物。 近年來,小膠質細胞除了對神經營養·保護作用以外,產生的NO、TNF- α、IL-1 β對神經傷害作用很受關注。西寶生物可提供日本和光Wako—神經退行性疾病研究—小膠質/巨噬細胞特異性蛋白抗Iba1抗體,咨詢訂購熱線:400-021-8158![查看]
http://m.baichuan365.com/Article/mzyxsjtxxjbyjxjzjsxb_1.html
【新品速遞】Cisbio 藥物靶標胞外激酶(Kinase)活性檢測整體解決方案
為了支持激酶類藥物的篩選、發現與開發,西寶生物攜手Cisbio為您提供多種激酶類型,從檢測方法優選、高通量篩選到選擇性分析等一系列激酶研究解決方案。Cisbio 激酶檢測,是基于抗體的檢測產物生成的解決方案,其特異性各不相同。包括基于 ADP 定 量的適用于所有激酶的 ADP Transcreener 檢測試劑盒;利用通用底物的經過兩百多種激酶驗證 的 KinEASE 試劑盒;利用特定底物、特異抗體的 HTRF 工具箱解決方案。[查看]
http://m.baichuan365.com/Article/cisbiobnjmhxjcztjjfa_1.html
Nat Commun:阿爾茲海默癥病理蛋白與小鼠的細胞死亡有關
一種與阿爾茨海默病(AD)有關的新蛋白質已被日本理化研究所腦科學中心(RIKEN CBS)的研究人員發現。CAPON可能促進兩個最著名的AD罪魁禍首--淀粉樣斑塊和tau病理之間的聯系,二者的相互作用會導致腦細胞死亡和癡呆癥狀。這一最新發現來自RIKEN CBS的Takaomi Saido小組,他們使用了一種新穎的小鼠AD模型,這項研究發表在《自然通訊》雜志上。[查看]
http://m.baichuan365.com/Article/natcommunaezhmzbldby_1.html
Science子刊:發現經常突變的癌蛋白的空間染色體組織的新作用
威斯達研究所的一項新研究揭示了蛋白質ARID1A的功能,該蛋白由一種基因編碼,這種基因是人類癌癥中最常見的突變之一。根據發表在《Science Advances》上的這項研究,ARID1A在基因組的空間組織中發揮著作用;因此,它的缺失對整體的基因表達具有廣泛的影響。這一發現為破譯與幾種癌癥特別是卵巢癌相關的分子變化提供了重要信息。[查看]
http://m.baichuan365.com/Article/sciencezkfxjctbdadbd_1.html
基因泰克創新<font color='red'>AD</font>C獲批治療早期乳腺癌 驗證臨床開發新模式
4日,基因泰克(Genentech)宣布,美國FDA批準其抗體偶聯藥物Kadcyla(ado-trastuzumab emtansine)擴大適應癥,作為術后輔助療法,治療HER2陽性,在接受新輔助療法治療后,依舊有殘余病灶的早期乳腺癌患者。這一療法的獲批,不但為早期乳腺癌患者提供了一款新的治療選擇,而且驗證了針對早期高危乳腺癌患者開展臨床試驗的新模式。[查看]
http://m.baichuan365.com/Article/jytkcxadchpzlzqrxayz_1.html
Science子刊:開發一種用于阿爾茨海默早期診斷癥的血液測試
韓國多家機構的一個大型研究團隊開發了一種全新的血液檢測方法,可以在尚未出現癥狀的早期階段檢測出老年癡呆癥患者。在這篇發表于《Science Advances》雜志上的論文中,該小組描述了他們的研究以及他們開發的檢測這種疾病的技術。[查看]
http://m.baichuan365.com/Article/sciencezkkfyzyyaechm_1.html
蜘蛛絲可以被用來制作“人造肌肉”?
研究人員最近發現了一種稱為“超收縮”的蜘蛛絲屬性,其中纖細的纖維可以隨著水分的變化而突然收縮。新的發現是,不僅螺紋收縮,它們同時扭曲,提供強大的扭轉力。 相關研究結果發表在《Science Advance》雜志上。[查看]
http://m.baichuan365.com/Article/zzskybylzzrzjr_1.html
間充質干細胞可用于修復器官損傷
在成人中,間充質干細胞(MSC)主要存在于骨髓中,它們在受損器官的修復中起重要作用。最近,由弗萊堡大學高分子化學研究所的Prasad Shastri教授和Melika Sarem博士領導的研究小組提出了自主控制MSCs軟骨形成的證據。這些發現發表在《Stem Cell Research & Therapy》雜志上。[查看]
http://m.baichuan365.com/Article/jczgxbkyyxfqgss_1.html
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Palladium 5% HCl (v/v) 1000ug/mL
Palladium 10,000ug/mL in 5% HCl
Palladium 10,000ug/mL in 5% HCl
Vanadium 2-5% HNO3 (v/v) 100ug/mL
Vanadium 2-5% HNO3 (v/v) 100ug/mL
Vanadium 2% HNO3 1,000ug/mL
Vanadium 2% HNO3 1,000ug/mL
Vanadium 2% HNO3 1,000ug/mL
Vanadium 2% HNO3 1,000ug/mL
Vanadium 2% HCl 1,000ug/mL
Vanadium 2% HCl 1,000ug/mL
Vanadium 2-5% HNO3 (v/v) 1000ug/mL
Vanadium 2-5% HNO3 (v/v) 1000ug/mL
Vanadium 2-5% HNO3 (v/v) 10000ug/mL
Vanadium 2-5% HNO3 (v/v) 10000ug/mL
Vanadium 15% HNO3 10,000ug/mL
Vanadium 15% HNO3 10,000ug/mL
Vanadium 15% HCl 10,000ug/mL
Vanadium 15% HCl 10,000ug/mL
Silver Vanadate
Silver Vanadate
Cadmium in 0.005% HNO3 1000ppm
Cadmium in 0.005% HNO3 1000ppm
Lead in 0.005% HNO3 1000ppm
Lead in 0.005% HNO3 1000ppm
Cadmium in 0.005% HNO3 1000ppm
Cadmium in 0.005% HNO3 1000ppm
Lead in 0.005% HNO31000ppm
Lead in 0.005% HNO31000ppm
Cadmium inin 0.005% HNO3 100ppm
Cadmium inin 0.005% HNO3 100ppm
Lead in 0.005% HNO3 1000ppm
Lead in 0.005% HNO3 1000ppm
17β-Estradiol
17β-Estradiol
Lead-Free Solder Chip(Sn96.5 Ag3 Cu0.5)-Pb High Concentration
Lead-Free Solder Chip(Sn96.5 Ag3 Cu0.5)-Pb High Concentration
n-Octadecyl 3-(3',5'-Di-t-butyl-4'-hydroxyphenyl)propionate Standard
n-Octadecyl 3-(3',5'-Di-t-butyl-4'-hydroxyphenyl)propionate Standard
Lead Acetate Solution (CH COO) Pb, 10%
Lead Acetate Solution (CH COO) Pb, 10%
Advanced ERK phospho-T202 /Y204 kit - 1 x 96 tests
Advanced ERK phospho-T202 /Y204 kit - 1 x 96 tests
Di(adenosine-5'-)penta-phosphate,trilithium salt
Di(adenosine-5'-)penta-phosphate,trilithium salt
Zwittergent 3-14,zwitterionic detergent, powder, N-Tetradecyl-N,N-dimethyl-3-ammonio-1-propane-sulfonate
Zwittergent 3-14,zwitterionic detergent, powder, N-Tetradecyl-N,N-dimethyl-3-ammonio-1-propane-sulfonate
氧化型輔酶I|煙酰胺腺嘌呤二核苷酸|53-84-9| β-NAD
氧化型輔酶I|煙酰胺腺嘌呤二核苷酸|53-84-9| β-NAD
Glucose dehydrogenase (NAD(P)-dependent)
Glucose dehydrogenase (NAD(P)-dependent)
Glutamate dehydrogenase(NADP dependent)
Glutamate dehydrogenase(NADP dependent)
Glutamate dehydrogenase (NAD dependent)
Glutamate dehydrogenase (NAD dependent)
Glutamate dehydrogenase (NADP dependent)
Glutamate dehydrogenase (NADP dependent)
ADP-dependent Hexokinase
ADP-dependent Hexokinase
ADP-dependent Hexokinase
ADP-dependent Hexokinase
Diaphorase (NADH)
Diaphorase (NADH)
Diaphorase (NADPH)
Diaphorase (NADPH)
NAD Synthetase
NAD Synthetase
Adenosine Deaminase,from calf intestine, suspension
Adenosine Deaminase,from calf intestine, suspension
Glutamate Dehydrogenase (NAD(P)),from E.coli overproducer, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from E.coli overproducer, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, chemically modified, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, chemically modified, lyophilizate
Glutamate Dehydrogenase (NAD(P)),from beef liver, solution
Glutamate Dehydrogenase (NAD(P)),from beef liver, solution
D-乳酸脫氫酶(D-LDH), Grade I
D-乳酸脫氫酶(D-LDH), Grade I
D-乳酸脫氫酶(D-LDH), Grade II
D-乳酸脫氫酶(D-LDH), Grade II
NAD(P)H Dehydrogenase (quinone) (Diaphorase),from pig heart, suspension
NAD(P)H Dehydrogenase (quinone) (Diaphorase),from pig heart, suspension
Liberase MTF C/T, GMP Grade,sterile filtered, lyophilizate
Liberase MTF C/T, GMP Grade,sterile filtered, lyophilizate
Liberase T-Flex, Research Grade,sterile filtered, lyophilizate
Liberase T-Flex, Research Grade,sterile filtered, lyophilizate
Endoproteinase Asp-N, Sequencing Grade,from a mutant of Pseudomonas fragi, lyophilizate
Endoproteinase Asp-N, Sequencing Grade,from a mutant of Pseudomonas fragi, lyophilizate
Endoproteinase Glu-C, Sequencing Grade,from Staphylococcus aureus V8, lyophilizate
Endoproteinase Glu-C, Sequencing Grade,from Staphylococcus aureus V8, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, lyophilizate
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution
Endoproteinase Lys-C, Sequencing Grade,from Lysobacter enzymogenes, solution
Glucose Dehydrogenase (NAD Dependent)
Glucose Dehydrogenase (NAD Dependent)
Glucose Oxidase (GOD), Grade I,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade I,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade II,from Aspergillus niger overproducer, lyophilizate
Glucose Oxidase (GOD), Grade II,from Aspergillus niger overproducer, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade I,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Lactate 2-Monooxygenase (Lactate oxidase), Grade II,from Aerococcus viridans, expressed in E. coli, lyophilizate
Peroxidase (POD), Grade II,from horse radish, lyophilizate
Peroxidase (POD), Grade II,from horse radish, lyophilizate
DADK嗪草酮標準品
DADK嗪草酮標準品
1-cis-3-Chloroallyl-3,5,7-triaza-1-azonia-adamantane chloride
1-cis-3-Chloroallyl-3,5,7-triaza-1-azonia-adamantane chloride
Oxadiargyl
Oxadiargyl
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
USP Solution Lead Acetate TS Conforms to USP 34
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate cotton
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopoeia Reagent Lead acetate paper
European Pharmacopeoia Lead Acetate Solution
European Pharmacopeoia Lead Acetate Solution
European Pharmacopoeia Reagent Molybdovanadic reagent
European Pharmacopoeia Reagent Molybdovanadic reagent
European Pharmacopoeia Reagent 0.1M Lead Nitrate
European Pharmacopoeia Reagent 0.1M Lead Nitrate
European Pharmacopoeia Reagent Concentrated to make Cadmium Standard sol. (0.1% Cd)
European Pharmacopoeia Reagent Concentrated to make Cadmium Standard sol. (0.1% Cd)
European Pharmacopoeia Lead Solution (0.1% Pb)
European Pharmacopoeia Lead Solution (0.1% Pb)
European Pharmacopoeia Reagent Concentrate to make Lead solution (100ppm Pb)
European Pharmacopoeia Reagent Concentrate to make Lead solution (100ppm Pb)
EDDP perchlorate (Methadone metabolite),100ug/mL (as pyrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),100ug/mL (as pyrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),1.0mg/mL (as pyrrolinium) 于甲醇
EDDP perchlorate (Methadone metabolite),1.0mg/mL (as pyrrolinium) 于甲醇
Loratadine impurity F
Loratadine impurity F
氧化鋁 (Reduction Grade) 標準物質
氧化鋁 (Reduction Grade) 標準物質
MAB<HCG>M-INN22-IgG Human chorionic gonadotropin b-chain
MABM-INN22-IgG Human chorionic gonadotropin b-chain